M
- M.A.N.T.I.S. (1994–1995), science fiction
- M.Y.O.B. (2000), comedy
- M Squad (1957–1960), crime drama
- MacGruder and Loud (1985), crime drama
- MacGyver (1985–1992), action/ adventure
- Mack & Myer for Hire (1963–1964), sitcom
- MAD (September 6, 2010 – present), animated sketch comedy
- Mad About You (1992–1999), sitcom
- Mad Love (2011), sitcom
- Mad Men (July 19, 2007 – present), period drama
- Made (April 22, 2002 – present), reality
- Madigan Men (2000), comedy
- Madman of the People (1994–1995), sitcom
- MADtv (1995–2009), sketch comedy
- Maggie (1998–1999), sitcom
- Maggie Winters (1998–1999), sitcom
- The Magic Clown (1949–1954), children's program
- Magical DoReMi (2005–2008, ended in 2006 on television), dubbed children's anime
- The Magic Garden (1972–1984), children's program
- The Magician (1973–1974), crime drama
- The Magnificent Seven (1998–1999), western
- Magnum, P.I. (1980–1988), mystery/ crime drama
- Major Dad (1989–1993), sitcom
- Make It or Break It (June 22, 2009 – present), drama
- Make Room for Daddy (1953–1964), sitcom
- Make Way for Noddy
- Make Room for Granddaddy (1970–1971), sitcom
- Making the Band (2000 – present), reality
- Making the Grade (1982), sitcom
- Malcolm & Eddie (1996–2000), sitcom
- Malcolm in the Middle (2000–2006), sitcom
- Malibu, CA (1998–2000), sitcom
- Malibu Shores (1996), drama
- Mama's Family (1983–1990), sitcom
- The Man and the City (1971–1972), drama
- A Man Called Hawk (1988–1989), action/ drama
- A Man Called Sloane (1979–1980), drama
- A Man Called Shenandoah (1965–1966), western
- Man from Atlantis (1977–1978), science fiction
- The Man from U.N.C.L.E. (1964–1968), espionage
- Man of the People (1991–1992), drama/ comedy
- The Man Show (1999–2004), sketch comedy
- Man with a Camera (1958–1960), crime drama
- Mancuso, F.B.I. (1989–1990), crime drama
- Manhattan, AZ (2000), mystery
- The Manhunter (1974–1975), crime drama
- Manimal (1983), drama/ action adventure
- Mann & Machine (1992), crime drama/ science fiction
- Mannix (1967–1975), crime drama
- The Many Loves of Dobie Gillis (1959–1963), sitcom
- Marcus Welby, M.D. (1969–1976), medical drama
- Marker (1990), drama
- The Marriage Ref (February 28, 2010 – present), reality
- Married People (1990–1991), sitcom
- Married to the Kellys (2003–2004), sitcom
- Married... with Children (1987–1997), sitcom
- The Marshal (1995), crime drama
- The Martha Stewart Show
- Martial Law (1998–2000), action/ crime drama
- Martin (1992–1997), sitcom
- The Martin Short Show (1994–1995), sketch comedy
- The Martin Short Show (1999), talk show
- Mary (1978), variety
- Mary (1985–1986), sitcom
- Mary Hartman, Mary Hartman (1976–1977), soap opera parody
- Mary Kay and Johnny (1947–1950), sitcom
- The Mary Tyler Moore Hour (1979), comedy
- Mary Tyler Moore (1970–1977), sitcom
- M*A*S*H (1972–1983), comedy/ medical drama
- The Mask: The Animated Series (1995–1997), animated comedy
- Masked Rider (1995–1996), action/ adventure
- The Master (1984), action/ adventure
- Masterpiece Theatre (January 10, 1971 – present), anthology
- Matlock (1986–1992), mystery/ legal drama
- Matt Helm (1975–1976), crime drama
- Matt Houston (1982–1985), crime drama
- Matt Lincoln (1970–1971), medical drama
- Maude (1972–1978), sitcom
- Maury (September 9, 1991 – present), talk show
- Maverick (1957–1962), western
- Max Headroom (1987–1988), cyberpunk/ drama
- Max Steel (2000–2002), animated science fiction
- Maximum Bob (1998), comedy/ drama
- Maybe It's Me (2001–2002), sitcom
- Maybe This Time (1995–1996), sitcom
- Mayberry R.F.D. (1968–1971), sitcom
- McBride (2005 – present), mystery/ thriller
- McClain's Law (1981–1982), crime drama
- McCloud (1970–1977), crime drama
- McCoy (1975–1976), action adventure
- McHale's Navy (1962–1966), sitcom
- McKenna (1994–1995), drama
- The McLaughlin Group (January 1, 1982 – Present), politics/ talk
- McMillan & Wife (1971–1977), crime drama
- MDs (2002), medical drama
- Me and the Boys (1994–1995), sitcom
- Medical Center (1969–1976), medical drama
- Medical Investigation (2004–2005), medical drama
- Medical Story (1975–1976), medical drama
- Medium (2005–2011), supernatural thriller
- Meego (1997), sitcom
- Meet My Folks (2002–2003), reality/ comedy
- Meet the Press (November 6, 1947 – present), public affairs/ news
- Meet the Browns (January 7, 2009 – present), sitcom
- Melissa & Joey (August 17, 2010 – present), sitcom
- Melrose Place (1992–1999), prime time soap
- Melrose Place (2009–2010), prime time soap
- Memphis Beat (June 22, 2010 –present), drama
- Men Behaving Badly (1996–1997), sitcom
- Men in Trees (2006–2008), comedy/ drama
- Men into Space (1959–1960), science fiction
- Men of a Certain Age (December 7, 2009 – July 6, 2011), comedy/ drama
- Men, Women & Dogs (2001), sitcom
- Mental (2009), medical drama
- The Mentalist (September 23, 2008 – present), police procedural
- Mercy (2009–2010), medical drama
- Mercy Point (1998–1999), science fiction
- The Merv Griffin Show (1962–1986), talk show
- Method & Red (2004), comedy
- Miami Medical (2010), medical drama
- Miami Vice (1984–1990), crime drama
- Michael Hayes (1997–1998), legal drama
- Michael Shayne (1960–1961), crime drama
- The Michael Richards Show (2000), sitcom
- The Mickey Mouse Club (1955–1959, 1977–1979, 1989–1996), children's variety
- Mickey Mouse Clubhouse (May 5, 2006 – present), animated
- Mickey Mouse Works (1999–2000), animated
- Mickey Spillane's Mike Hammer (1958–1960), crime drama
- Mickey Spillane's Mike Hammer (1984–1985), crime drama
- The Middle (September 30, 2009 – present), sitcom
- Midnight Caller (1988–1991), drama
- The Midnight Special (1973–1981), music variety
- The Mighty Heroes (1966–1967), cartoon
- Mighty Max (1993–1994), cartoon
- Mighty Morphin Power Rangers (1992–1994), children's/ action
- Mighty Mouse: The New Adventures (1987–1988), animated
- Mike & Molly (September 20, 2010 – present), sitcom
- The Mike Douglas Show (1961–1982), talk show
- Mike Hammer, Private Eye (1997–1998), crime drama
- The Mike O'Malley Show (1999), sitcom
- Millennium (1996–1999), thriller/ horror
- Million Dollar Money Drop (2010–2011) game show
- Mind of Mencia (2005–2008), stand–up & sketch comedy
- The Mind of the Married Man (2001–2002), drama/ comedy
- The Minor Accomplishments of Jackie Woodman (2006–2007), comedy
- Minor Adjustments (1995–1996), sitcom
- Mira Quien Baila (September 12, 2010 – present), dance/reality
- Miracles (2003), horror/ thriller
- The Misadventures of Sheriff Lobo (1979–1981), action adventure/ comedy
- Misfits of Science (1985–1986), science fiction
- Miss Guided (2008), sitcom
- Miss Match (2003), dramedy
- Mission Hill (1999–2002), animated sitcom
- Mission: Impossible (1966–1973), espionage
- Mission: Impossible (1988–1990), espionage
- The Mississippi (1983–1984), drama
- Mister Ed (1961–1966), sitcom
- Mister Rogers' Neighborhood (1968–2001), children's program
- Mister Sterling (2003), political drama
- Mobile One (1975), crime drama
- The Mod Squad (1968–1973), crime drama
- Models Inc. (1994–1995), prime time soap
- Modern Family (September 23, 2009 – present), sitcom
- Modern Marvels (January 1, 1995 – present), documentary
- Modern Men (1996), sitcom
- Moesha (1996–2001), sitcom
- The Mole (2001–2008), reality/ game show
- Moloney (1996–1997), drama
- The Mommies (1993–1995), sitcom
- Monarch Cove (2006), drama
- Monday Night Football (September 21, 1970 – present), sports
- Monk (2002–2010), police procedural/ comedy
- The Monkees (1966–1968), sitcom/ music
- The Monroes (1966–1967), western
- The Monroes (1995), prime time soap opera
- Monster Squad (1976–1977), comedy adventure
- Monsters (1988–1991), horror anthology
- The Montefuscos (1975), sitcom
- The Montel Williams Show (1991–2008), talk show
- Monty (1994), sitcom
- Moon Over Miami (1993), comedy
- Moonlight (2007–2008), supernatural horror
- Moonlighting (1985–1989), drama/ comedy
- More to Love (2009), reality/ game
- Mork & Mindy (1978–1982), sitcom
- Morning Joe (May 9, 2007 – present), talk show
- The Most Deadly Game (1970–1971), drama
- The Mothers-in-Law (1967–1969), sitcom
- Mountain (2007–2005), drama
- Movin' On (1974–1976), drama
- Mr. & Mrs. Smith (1996), crime drama
- Mr. Belvedere (1985–1990), sitcom
- Mr. Lucky (1959–1960), drama/ adventure
- The Mr. Magoo Show (1964–1966), cartoon
- The Mr. Men Show (2008–2009), animated children's program
- Mr. Merlin (1981–1982), sitcom
- Mr. Peepers (1952–1955), sitcom
- Mr. Rhodes (1996–1997), sitcom
- Mr. Show (1995–1998), sketch comedy
- Mr. Smith (1983), sitcom
- Mr. Smith Goes to Washington (1962–1963), sitcom
- Mr. Sunshine (2011), comedy
- Mr. T and Tina (1976), sitcom
- Mr. Terrific (1967), sitcom
- Mrs. Columbo (1979–1980), mystery
- MTV Cribs (October 5, 2000 – present), reality
- Muddling Through (1994), sitcom
- The Mullets (2003–2004), sitcom
- The Munsters (1964–1966), sitcom
- The Munsters Today (1988–1991), sitcom
- The Muppet Show (1976–1981), variety/ comedy
- Muppets Tonight (1996–1998), comedy
- Murder 101 (2006–2008), mystery/ thriller
- Murder in Small Town X (2001), reality/ mystery
- Murder One (1995–1997), crime drama
- Murder, She Wrote (1984–1996), mystery
- Murphy Brown (1988–1998), sitcom
- Murphy's Law (1988–1989), comedy/ drama
- The Music Scene (1969–1970), music/ variety
- Muscle (1995), sitcom
- M-U-S-H (1975–1976), cartoon
- Mutant X (2001–2004), science fiction
- My Antonio (2009), reality/ docu-soap
- My Big Fat Greek Life (2003), sitcom
- My Big Fat Obnoxious Fiance (2004), reality
- My Boys (2006–2010), sitcom
- My Fair Brady (2005–2008), reality
- My Favorite Martian (1963–1966), sitcom/ fantasy
- My Generation (September 23, 2010–September 30, 2010), mockumentary
- My Life as a Teenage Robot (2003–2009), animated comedy
- My Little Pony: Friendship is Magic (October 10, 2010 – present), animated series
- My Living Doll (1964–1965), sitcom/ science fiction
- My Mother the Car (1965–1966), sitcom
- My Name Is Earl (2005–2009), sitcom
- My Own Worst Enemy (2008), drama
- My Secret Identity (1988–1991), science fiction
- My Sister Sam (1986–1988), sitcom
- My So-Called Life (1994–1995), teen drama
- My Super Sweet 16 (2005–2008), reality
- My Three Sons (1960–1972), sitcom
- My Two Dads (1987–1990), sitcom
- My Wife and Kids (2001–2005), sitcom
- My World and Welcome to It (1969–1970), sitcom
- Mystery! (1980 – present), episodic drama
- Mystery Science Theater 3000 (1988–1999), comedy
- Mystery Woman (2003–2007), mystery
- MythBusters (January 23, 2003 – present), documentary/ science
Read more about this topic: List Of American Television Series