I
- I Dream of Jeannie (1965–1970), sitcom
- I Love Lucy (1951–1957), sitcom
- I Love New York (2007–2008), reality
- I Married Joan (1952–1955), sitcom
- I, Max (2004–2005), sports commentary
- I Pity the Fool (2006), reality
- I Spy (1965–1968), espionage
- I Survived a Japanese Game Show (2008–2009), reality/ game show
- I'll Fly Away (1991–1993), drama
- I'm With Busey (2003), comedy/ documentary
- I'm With Her (2003–2004), sitcom
- I've Got a Secret (1953–1967), game show
- iCarly (September 8, 2007 – November 23, 2012), sitcom
- Ice Road Truckers (June 17, 2007 – present), documentary
- The Imogene Coca Show (1954–1955), comedy/variety
- In Justice (2006), police procedural
- In Living Color (1990–1994), sketch comedy
- In Plain Sight (June 1, 2008 – present), drama
- In Search Of... (1976–1982), documentary
- In the Heat of the Night (1988–1995), crime drama
- In the Motherhood (2009), sitcom
- In Treatment (2008–2010), drama
- Inch High, Private Eye (1973–1974), cartoon
- Inconceivable (2005), medical drama
- The Incredible Hulk (1977–1982), sci-fi/ action
- Ink (1996–1997), sitcom
- Inside Edition (October 9, 1988 – present), news magazine
- Inside the Actors Studio (August 14, 1994 – present), talk show
- Inside the NFL (September 14, 1977 – present), sports
- Insomniac with Dave Attell (2001–2004), comedy/ talk show
- Inspector Gadget (1983–1986), animated comedy
- The Invaders (1967–1968), sci-fi
- Invader Zim (2001–2006), animated comedy
- Invasion (2005–2006), sci-fi
- Invasion America (1998), animated science fiction
- The Invisible Man (1975–1976), sci-fi
- The Invisible Man (2000–2002), sci-fi/ action
- Iron Chef (1993–1999), cooking
- Iron Man (1994–1996), cartoon
- Ironside (1967–1975), crime drama
- The Islanders (1960–1961), adventure
- It Had to Be You (1993), sitcom
- It Takes a Thief (1968–1970), action adventure
- It Takes a Thief (2005–2007), reality
- It's a Living (1980–1982, 1985–1989), sitcom
- It's All Relative (2003–2004), sitcom
- It's Always Sunny in Philadelphia (August 4, 2005 – present), sitcom
- It's Garry Shandling's Show (1986–1990), sitcom
- It's Like, You Know... (1999–2000), sitcom
- It's Your Chance of a Lifetime (2000), game show
- It's Your Move (1984–1985), sitcom
Read more about this topic: List Of American Television Series