D
- Daddio (2003), sitcom
- DAG (2000–2001), sitcom
- The Daily Show (July 22, 1996 – present), satire/news parody
- Daktari (1966–1969), children's drama
- Dallas (1978–1991), prime time soap drama
- Damage Control (2005), reality
- Damages (July 24, 2007 – present), legal drama
- Dan August (1970–1971), crime drama
- The Dana Carvey Show (1996), sketch comedy
- Dance Fever (1979–1987), music
- Dance on Sunset (2008), children's dance series
- Dancing with the Stars (June 1, 2005 – present), reality
- Daniel Boone (1964–1970), adventure
- The Danny Thomas Show (1953–1964), sitcom
- Dante's Cove (October 7, 2005), soap opera/ supernatural
- Daria (1997–2002), animated comedy
- Dark Angel (2000–2002), sci-fi/action
- Dark Blue (2009–2010), drama/ thriller
- Dark Realm (2001), anthology
- Dark Shadows (1966–1971), sci-fi soap
- Dark Shadows (1991), sci-fi/ thriller
- Dark Skies (1996–1997), sci-fi
- Date My Mom (2004–2006), reality
- Date with the Angels (1957–1958), sitcom
- Dateline NBC (March 31, 1992 – present), news magazine
- The Dating Game (1965–1999), game show
- Dave the Barbarian (2004–2005), cartoon
- Dave's World (1993–1997), sitcom
- Davey and Goliath (1960–1975), clay animation children's series
- The David Letterman Show (1980), talk show
- Davy Crockett (1954–1955), adventure
- Dawson's Creek (1998–2003), teen drama
- Day Break (2006), thriller
- Day by Day (1988–1990), sitcom
- The Days (2004), drama
- The Days and Nights of Molly Dodd (1987–1991), comedy/drama
- Days of our Lives (November 8, 1965 – present), soap opera
- Dead Last (2001), drama/ fantasy/ comedy
- Dead Like Me (2003–2004), sci-fi/comedy-drama
- The Dead Zone (2002–2007), sci-fi / crime drama
- Deadliest Catch (April 12, 2005 – present), documentary/ reality
- Deadly Games (1995–1997), sci-fi
- Deadwood (2004–2006), western
- Deal or No Deal (2005–2009), game show
- The Dean Martin Show (1965–1974), variety
- Dear John (1988–1992), sitcom
- Death Valley Days (1952–1975), western anthology
- The Debbie Reynolds Show (1969–1970), sitcom
- Def Comedy Jam (1992–1997, 2006–present), stand up comedy
- The Defenders (1961–1965), crime drama
- The Defenders (2010–2011), legal drama
- Delta House (1979), sitcom
- Delvecchio (1976–1977), crime drama
- The Dennis O'Keefe Show (1959–1960), sitcom
- Dennis Miller Live (1994–2002), talk show/ comedy
- The Dennis Miller Show (1992), talk show
- Dennis the Menace (1959–1963), sitcom
- Dennis the Menace (1986–1988), cartoon
- Deputy Dawg (1959–1972), animated series
- Desire' (2006), telenovela
- Designing Women (1986–1993), sitcom
- Desperate Housewives (October 3, 2004 – May 13, 2012 ), drama/ comedy
- Detroit 1-8-7 (2010–2011), crime drama
- Dexter (October 1, 2006 – present), psychological thriller
- Dharma and Greg (1997–2002), sitcom
- Diagnosis: Murder (1993–2001), mystery
- The Dick Cavett Show (1968–1975), talk show
- The Dick Clark Show (1958–1960), music
- Dick Clark's New Year's Rockin' Eve (December 31, 1972 - December 31, 2011), variety
- The Dick Tracy Show (1961–1962), animated series
- The Dick Van Dyke Show (1961–1966), sitcom
- A Different World (1987–1993), sitcom
- Diff'rent Strokes (1978–1986), sitcom
- Dilbert (1999–2000), animated series
- Dinah! (1974–1980), talk show
- The Dinah Shore Chevy Show (1955–1963), variety
- The Dinah Shore Show (1951–1956), variety
- Dinosaurs (1991–1994), sitcom
- DinoSquad (2007–2009), cartoon
- Dirt (2007–2008), talk show
- Dirty Jobs (July 26, 2005 – present), reality
- Dirty Sexy Money (2007–2009), drama
- Dismissed (2001–2004), reality
- The District (2000–2004), crime drama
- The Division (2001–2004), crime drama
- Divorce Court (1957–1969, 1985–1992, 2006–present), reality
- Do Not Disturb (2008), sitcom
- Do Over (2002), fantasy/ comedy
- Doc (1975–1976), sitcom
- Doc (2001–2004), western
- Doctor Doctor (1989–1991), sitcom
- Dr. Phil (September 16, 2002 – present), talk show
- Dr. Quinn, Medicine Woman (1993–1998), western
- Dog Eat Dog (2002–2003), game show
- Dog the Bounty Hunter (August 31, 2004 – present), reality
- Dollhouse (2009–2010), science fiction/ thriller
- Dolly (1987–1988), variety
- Dolly! (1976–1977), variety
- The Donna Reed Show (1958–1966), sitcom
- Donny & Marie (1976–1979), variety
- Donny & Marie (1998–2000), talk show
- Don't Forget the Lyrics! (2007–2009, 2010–2011), game show
- Doogie Howser, M.D. (1989–1993), comedy/drama
- Dora the Explorer (August 14, 2000 – present), animated
- The Doris Day Show (1968–1973), sitcom
- Dot Comedy (2000), sitcom
- Double Dare (1976–1977), game show
- Double Dare (1986–1993), children's game show
- Double Dare 2000 (2000), children's game show
- Double Trouble (1984–1985), sitcom
- Doug (1991–1999), animated comedy
- Dragnet (1951–1959, 1967–1970), crime drama
- Dragons: Riders of Berk (August 7, 2012 – present), 3D animated comedy
- Drake & Josh (2004–2007), teen sitcom
- Drawn Together (2004–2007), animated comedy
- Dream On (1990–1996), sitcom
- The Dresden Files (2007), supernatural/ mystery
- The Drew Carey Show (1995–2004), sitcom
- Drew Carey's Green Screen Show (2004–2005), comedy
- Drexel's Class (1991–1992), sitcom
- Drive (2007), action/ drama
- Drop Dead Diva (July 12, 2009 – present), fantasy/ dramedy
- Due South (1994–1999), comedy/ drama
- The Dukes of Hazzard (1979–1985), action/comedy
- Dusty's Trail (1973–1974), western/comedy
- Dynasty (1981–1989), prime time soap drama
Read more about this topic: List Of American Television Series