C
- C.P.O. Sharkey (1976–1978), sitcom
- Cade's County (1971–1972), crime drama
- Caillou
- Caitlin's Way (2000–2004), teen drama
- Cagney & Lacey (1985–1988), crime drama
- Californication (August 13, 2007 – present), comedy / drama
- Cake (2006), sitcom
- California Dreams (1992–1996), sitcom
- Camelot (2011), historical drama
- Camouflage (2007), game show
- Camp Lazlo (2005–2008), animated
- Candid Camera (1948–2004), hidden-camera/ reality
- Cane (2007), drama
- Cannon (1971–1976), crime drama
- Canterbury's Law (2008), legal drama
- The Cape (2011), superhero/ crime drama
- Capital News (1990), drama
- Captain Kangaroo (1955–1984), children
- Car 54, Where Are You? (1961–1963), sitcom
- Card Sharks (1978–1981, 1986–1989, 2001–2002), game show
- The Care Bears (1985–1988), cartoon
- Carnivàle (2004–2005), thriller mystery
- Carol & Company (1990–1991), sketch comedy
- The Carol Burnett Show (1967–1978), sketch comedy/ variety
- Caroline in the City (1995–1999), sitcom
- The Caroline Rhea Show (2002–2003), talk show
- Carpoolers (2007–2008), sitcom
- Carter Country (1977–1979), sitcom
- Cartoon Alley (2004–2007), cartoon anthology
- Cash Cab (December 5, 2005 – present), game show
- Cashmere Mafia (2008)
- Casper the Friendly Ghost (1963–1969), cartoon
- Castle (March 9, 2009 – present), police procedural
- Cavemen (2007), sitcom
- Cedric the Entertainer Presents (2002–2003), sketch comedy
- Celebrities Uncensored (2003–2004), reality/ news
- Celebrity Circus (2008), reality
- Celebrity Deathmatch (1998–2002, 2006–2007), claymation
- Celebrity Sweepstakes (1974–1977), game show
- Center of the Universe (2004–2005), sitcom
- Central Park West (1995–1996), drama
- Century City (2004–2005), sci fi/ legal drama
- Chain Reaction (1980, 1986–1991, 2006–2007), game show
- The Chamber (2002), game show
- Chappelle's Show (2003–2006), sketch comedy
- Charlie Rose (September 30, 1991 – present), talk show
- Charlie's Angels (1976–1981), crime drama
- Charles in Charge (1984–1990), sitcom
- Charmed (1998–2006), supernatural drama
- The Charmings (1987–1988), fantasy sitcom
- Chase (1973–1974), crime drama
- Chase (2010–2011), crime drama
- Cha$e (2008), reality game show
- Chasing Farrah (2005), reality
- Cheaters (October 21, 2000 – present), reality
- Checking In (1981), sitcom
- Cheers (1982–1993), sitcom
- The Chelsea Handler Show (2006), sketch comedy
- Cheyenne (1955-1963), western
- Chelsea Lately (July 16, 2007 – present), talk show
- The Chicago Code (2011). crime drama
- Chicago Hope (1994–2000), medical drama
- Chico and the Man (1974–1978), sitcom
- China Beach (1988–1991), war drama
- CHiPs (1977–1983), crime drama
- The Chris Isaak Show (2001–2004), sitcom
- The Chris Rock Show (1997–2000), comedy
- Chuck (September 24, 2007 – present), action / comedy
- Citizen Baines (2001), drama
- The City (1995–1997), soap opera
- The City (2008–2010), reality
- City Confidential (1999–2006), documentary
- City Guys (1997–2001), sitcom
- City of Angels (1976), crime drama
- City of Angels (2000), medical drama
- The Class (2006–2007), sitcom
- Class of '96 (1993), drama
- Class of 3000 (2006–2008), animated
- The Cleaner (2008–2009), drama
- Cleopatra 2525 (2000–2001), science fiction
- The Cleveland Show (September 27, 2009 – present), animated
- Clone High (2002–2003), animated
- Close to Home (2005–2007), crime/ legal drama
- The Closer (June 13, 2005 – present), crime drama
- Clubhouse (2004), drama
- Co-Ed Confidential (November 2, 2007 – present), erotica
- Co-Ed Fever (1979), sitcom
- Coconut Fred's Fruit Salad Island (2005–2006), cartoon
- Code Red (1981-1982), drama
- Cold Case (2003-2010), drama
- The Colbert Report (October 17, 2005 – present), satire
- The Colbys (1985–1987), prime time soap opera
- Cold Pizza (2003–2007), sports
- Colgate Comedy Hour (1950–1955), variety
- The CollegeHumor Show (2009–2010), comedy
- Combat! (1962–1967), war drama
- Combat Hospital (21 June 2011 – present), medical drama
- Comeback (2005), sitcom
- Comedy Central Presents (December 1, 1998 – present), stand-up comedy
- Commander in Chief (2005–2006), political drama
- Committed (2005), sitcom
- Community (September 17, 2009 – present), sitcom
- Complete Savages (2004–2005), sitcom
- Conan (November 8, 2010 – present), talk show / comedy
- "Conspiracy Theory with Jesse Ventura" (2009 - present), documentary / reality
- The Contender (March 7, 2005 – present), sports / reality
- Conviction (2006), legal drama
- Cop Rock (1990), crime drama/ musical
- COPS (March 11, 1989 – present), reality/ documentary
- Cory In The House (2007–2008), sitcom
- Cos (1976), variety
- Cosby (1996–2000), sitcom
- The Cosby Mysteries (1994–1995), mystery/ drama
- The Cosby Show (1984–1992), sitcom
- Cougar Town (September 23, 2009 – present), sitcom
- Countdown with Keith Olbermann (2007–2011), political commentary
- Coupling (2003), sitcom
- Courageous Cat and Minute Mouse (1960–1962), animated
- Courting Alex (2006), sitcom
- The Courtship of Eddie's Father (1969–1972), sitcom
- Cousin Skeeter (1998–2003), sitcom
- Covert Affairs (July 13, 2010 – present), action/ drama
- Cracking Up (2004), sitcom
- Crank Yankers (2002–2007), comedy
- Crash (2008–2010), drama
- Crime Story (1986–1988), crime drama
- Criminal Minds (September 22, 2005 – present), police procedural
- The Crocodile Hunter (1997–2004), wildlife/ documentary
- Crossing Jordan (2001–2007), crime drama
- Crossroads (1955–1957), anthology/ drama
- Crusade (1999), sci-fi
- CSI: Crime Scene Investigation (October 6, 2000 – present), police procedural
- CSI: Miami (September 23, 2002 – present), police procedural
- CSI: New York (September 22, 2004 – present), police procedural
- Cupid (1998–1999), dramedy
- Cupid (2009), dramedy
- Curb Your Enthusiasm (October 15, 2000 – present), comedy
- A Current Affair (1986–1996, 2005), news magazine
- Cursed (2000–2001), sitcom
- Cuts (2005–2006), sitcom
- Cyberchase (2006 - present), animated educational series
Read more about this topic: List Of American Television Series