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- Deepika Padukone as Sakhi/Ms. TSM and Suzy/Meow Meow in "Chandni Chowk to China"
- Michael Palin as Sir Galahad the Pure, First Swallow-Savvy Guard, Dennis, Peasant #2, the King of Swamp Castle, Brother Maynard's Brother, and the Leader of The Knights who say NI! in Monty Python and the Holy Grail (1975)
- Cezary Pazura as Jerzy Kiler and José Arcadio Morales in Kiler-ów 2-óch
- Tyler Perry as Daddy Charles and Mable "Madea" Simmons in Diary of a Mad Black Woman (2005)
- Mary Pickford as Stella Maris and Unity Blake in Stella Maris (1918)
- Jeremy Piven as The Time Keeper (Danger D'Amo), Danger's Father, and Tick Tock in Spy Kids: All the Time in the World.
- Natalie Portman as Ines and Ines' daughter Alicia in Goya's Ghosts (2006)
- Elvis Presley as Josh Morgan and Jodie Tatum in Kissin' Cousins (1964)
- Dennis Price as Louis Mazzini and his father in Kind Hearts and Coronets (1949)
- Vincent Price as Charles Dexter Ward and Joseph Curwen in The Haunted Palace (1963)
- Richard Pryor as Leroy Jones, Rufus Jones, and Reverend Lenox Thomas in Which Way Is Up? (1977)
- Prithviraj as Kelu and Krishnadas in Urumi
Read more about this topic: List Of Actors Who Have Played Multiple Roles In The Same Film