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- Nicolas Cage as Charlie Kaufman and Donald Kaufman in Adaptation. (2002)
- John Candy as Dennis Valkenheiser and Eldona in Nothing but Trouble (1991)
- Richard Chamberlain as Louis XIV and Phillipe in The Man in the Iron Mask (1977)
- David Carradine as The Blind Man, Monkeyman, Death, and Changsha in Circle of Iron (1978)
- Jackie Chan as Ma Yau (John Ma) and Die Hard (Boomer) in The Twin Dragons (1992)
- Lon Chaney played dual roles in several films, using the elaborate makeup that became his trademark.
- Charlie Chaplin as Adenoid Hynkel and a Jewish barber in The Great Dictator (1940)
- Graham Chapman as Brian, Biggus Dickus, and Wise Man #2 in Monty Python's Life of Brian (1979)
- Tommy Chong as Chong and Prince Habib in Things Are Tough All Over (1982)
- Priyanka Chopra as Anjali, Vishakha, Kajal, Hansa, Mallika, Pooja, Rajni, Nandini, Bhavna, Jhankhana, Sanjana & Chandrika in What's Your Raashee? (2009)
- Julie Christie as Mildred Montag and Clarisse McClellan in Fahrenheit 451 (1966)
- John Cleese as Sir Lancelot the Brave, The Black Knight, Tim the Enchanter, Second Swallow-Savvy Guard, Peasant #3 and Taunting French Guard in Monty Python and the Holy Grail (1975)
- John Cleese as Reg, Wise Man #1, a Jewish Official, a Centurion, Deadly Dirk, and Arthur in Monty Python's Life of Brian (1979)
- Sacha Baron Cohen as President Prime Minister Admiral General Haffaz Aladeen/Alison Burgers and his double Efawadh in The Dictator.
- Ronald Colman as Rudolf Rassendyll and King Rudolf V in The Prisoner of Zenda (1937)
- Dominic Cooper as Uday Hussein and Latif Yahia in The Devil's Double (2011)
- Marion Cotillard as Marie and Lucie in Pretty Things (2001)
- Buster Crabbe played dual roles in several films, most often as the lookalike villain in his string of "Billy Carson" westerns.
- Harry Crocker as Rex (a tightrope walker), a disgruntled property man and a clown in The Circus (1928)
Read more about this topic: List Of Actors Who Have Played Multiple Roles In The Same Film