LS
- L.S. – (i) Lectori Salutem (Latin, "greetings to the reader"; when the name of the reader is not known in advance)
- LS
- (i) Landing Support
- (s) Lesotho (ISO 3166 digram)
- Liechtenstein (FIPS 10-4 country code)
- (i) locus sigilli (Latin, "place of the seal")
- LSAT – (i) Law School Admission Test (often pronounced as "el-SAT")
- LSD
- (i) Landing Ship, Dock (Navy hull classification)
- librae, solidii, denarii (Latin: Pounds, shillings and pence)
- lyserg-saüre-dietylamid (German "lysergic acid diethylamide")
- LSE
- (i) Least Squares Estimate/Error
- London School of Economics
- London Stock Exchange
- LSI – (i) Large-Scale Integration
- LSIF – (i) Labour Sponsored Investment Fund
- LSL – (s) Lesotho loti (ISO 4217 currency code)
- LSND – (i) Liquid Scintillator Neutrino Detector
- LSO – (s) Lesotho (ISO 3166 trigram)
- LSST – (i) Large Synoptic Survey Telescope
- LST – (i) Landing Ship, Tank (World War II; also known, not entirely affectionately, as "Large Slow Target")
- LSVW – (i) Light Support Vehicle, Wheeled
Read more about this topic: List Of Acronyms And Initialisms: L