LIMA1

Identifiers Symbols LIMA1; EPLIN; SREBP3 External IDs OMIM: 608364 MGI: 1920992 HomoloGene: 9484 GeneCards: LIMA1 Gene

Gene Ontology
Molecular function	• actin monomer binding • zinc ion binding • metal ion binding • actin filament binding
Cellular component	• stress fiber • cytoplasm • plasma membrane • focal adhesion • actin cytoskeleton
Biological process	• negative regulation of actin filament depolymerization • ruffle organization • actin filament bundle assembly
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 51474 65970 Ensembl ENSG00000050405 ENSMUSG00000023022 UniProt Q59FE8 Q8C3R7 RefSeq (mRNA) NM_001113546 NM_001113545 RefSeq (protein) NP_001107018 NP_001107017 Location (UCSC) Chr 12:
50.57 – 50.68 Mb Chr 15:
99.78 – 99.88 Mb PubMed search

LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene.

EPLIN is a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles (Maul et al., 2003).