Notable American Lieutenant Colonels
- Robert L. Bacon (US Army)
- Scott Brown (Army National Guard)
- Aaron Burr (Continental Army)
- Joshua Chamberlain (US Army)
- Robert G. Cole (US Army)
- Jerry Coleman (United States Marine Corps)
- David P. Cooley (US Air Force)
- Bruce P. "Snake" Crandall (US Army), Medal of Honor recipient for his actions at Ia Drang, portrayed during his majority by Greg Kinnear in the film, We Were Soldiers
- George A. Custer (US Army), portrayed by numerous actors
- James Harold "Jimmy" Doolittle (US Air Force), Medal of Honor recipient for his raid on Tokyo, portrayed by Spencer Tracy in the film Thirty Seconds Over Tokyo and Alec Baldwin in the film Pearl Harbor
- Tammy Duckworth (US Army), Democratic Congresswoman (IL-8)
- Rick Francona (US Air Force)
- John C. Fremont (US Army)
- Gregory D. Gadson (US Army) bilateral above-the-knee amputee, occasional actor and motivational speaker.
- Virgil I. "Gus" Grissom (US Air Force), portrayed by Fred Ward in the film The Right Stuff, Steve Bernie in the film Apollo 13, Bryan Cranston in the film That Thing You Do!, Mark Rolston in the HBO miniseries From the Earth to the Moon, and by Kevin McCorkle in the third season finale of the NBC television series American Dreams
- Iceal Hambleton (US Air Force), portrayed by Gene Hackman in the film, Bat-21
- Anthony B. Herbert (US Army)
- Jon S. Jackson (US Army), served as defense lawyer at Guantanamo Bay for detainees Majid Khan (detainee), Omar Khadr, and Mustafa Hawsawi
- Gus Kohntopp (Air National Guard)
- ((Gerald Lambert)) (US Army)
- Oliver North (US Marine Corps)
- Ellison Shoji Onizuka (US Air Force)
- Ralph Peters (US Army)
- Rob Riggle (US Marine Corps)
- Rick Smith (US Army North Dakota National Guard)
- Ronald Speirs (US Army)
- Michael Strobl (US Marine Corps), portrayed by Kevin Bacon in the HBO film, Taking Chance.
- William Travis (Texas Militia)
- Matt Urban (US Army)
- John Paul Vann (US Army), portrayed by Bill Paxton in the HBO film, A Bright Shining Lie
- Edward Higgins White (US Air Force)
- Earl Woods (US Army)
- Philip Corso (US Army)
- Christopher B. Howard (US Air Force)
- Hal Moore (US Army) Famous for his actions at Ia Drang, portrayed by Mel Gibson in the film, We Were Soldiers
- Allen West (US Army)
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