Libido - Endogenous Substances Involved in Sex Drive

Endogenous Substances Involved in Sex Drive

See also: Sexual motivation and hormones, Sexual arousal#Hormones, and Sexual desire#Hormones
  • 5-HT1A agonist, as stabilizer; endogenously by serotonin (see below)
  • Acetylcholine
  • Androgens: testosterone
  • Cortisol
  • Dopamine
  • Estradiol
  • Estrogens
  • MC4R agonist; endogenously by α-Melanocyte-stimulating hormone
  • Norepinehrine, positively or negatively
  • Oxytocin
  • Progesterone, negatively; increased during the week following ovulation
  • Serotonin, negatively or positively. Low libido is a common side effect with selective serotonin reuptake inhibitors, but decrease in sexual desire may occur due to imbalance between excitatory neurotransmitters and inhibitory neurotransmitters, such as serotonin.
  • Sex hormone-binding globulin, negatively

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