LEZ may refer to:
- Derogative word form lesbian (more commonly les)
- Low emission zone
- IATA code for La Esperanza Airport in La Esperanza, Honduras
Lez may refer to:
- Lez, Haute-Garonne, a commune in Haute-Garonne département, France
- Lez river, a river in Hérault département, France
- Lez Duly, former member of punk band Concrete Sox
- ISO 639 code for Lezgian language