Leko may refer to:
- Leko (DJ), American DJ and producer
- Leko languages, a small group of African Savanna languages
- Lekolite or Leko, a type of stage spotlight
- Alexandro da Silva Santos or Leko, Brazilian footballer
- Leko (Arnarvon Islands), a minor island in the Arnarvon Islands
- People with the surname
- Dimitrije T. Leko (1863-1914), Serbian architect
- Ivan Leko (born 1978), Croatian footballer
- Jerko Leko (born 1980), Croatian footballer
- Marko Leko (1853-1932), Serbian chemist and president of the Serbian Red Cross
- Peter Leko (born 1979), Hungarian chess player
- Stefan Leko (born 1974), German-Croatian kickboxer