Legendre, LeGendre or Le Gendre is a French surname. It may refer to:
- Adrien-Marie Legendre (1752–1833), a French mathematician
- Legendre (crater), a lunar impact crater located near the eastern limb of the Moon
- 26950 Legendre, a main-belt asteroid discovered on May 11, 1997
- Anne Legendre Armstrong (1927–2008), a United States diplomat and politician
- Charles Le Gendre (1830–1899), a French-born American general and diplomat
- François Legendre (1763–1853), a surveyor, seigneur and political figure in Lower Canada
- Gertrude Sanford Legendre (1902–2000), an American socialite who served as a spy during World War II
- Jacques Legendre, several people
- Louis Legendre (1752–1797), a French politician of the Revolution period
- Pierre Legendre (born 1930), a French historian of law and psychoanalyst
- Richard Legendre (born 1953), a former professional tennis player and a Quebec politician
- Robert LeGendre (1898–1931), an American athlete
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