LEF
- LEF,the Laymen's evangelical fellowship, a Christian organisation.
- LEF, the Leading Edge Forum, a research and advisory service.
- LEF, the Lymphoid enhancer-binding factor 1.
- LEF (journal), a journal of aesthetics published in the Soviet Union in the 1920s.
- Library Exchange Format in Electronic design automation domain.
- Life Extension Foundation, a non-profit organization
- Long Edge Feed, a direction to feed paper to printers. Also used in combination with the paper size, e.g. A4 LEF
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