Cast
- Edward Norton as identical twins Bill and Brady Kincaid.
- Richard Dreyfuss as Pug Rothbaum, a business partner of Brady's.
- Susan Sarandon as Daisy Kincaid, Bill and Brady's mother.
- Keri Russell as Janet, a friend of Brady's and Bill's new romantic interest.
- Tim Blake Nelson as Rick Bolger, Brady's best friend.
- Melanie Lynskey as Colleen, Brady's pregnant girlfriend.
- Steve Earle as Buddy Fuller, a rival drug dealer of Brady's.
- Lucy DeVito as Anne, a student in love with Bill.
- Lee Wilkof as Nathan Levy, Bill's prospective boss at a new university.
- Ken Cheeseman as Jimmy Fuller, a rival drug dealer of Brady's.
- Maggie Siff as Rabbi Renannah Zimmerman
- Josh Pais as Ken Feinman
- Ty Burrell as Professor Sorenson
- Pruitt Taylor Vince as Big Joe Sharpe
- Randal Reeder as Shaver
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