Lapierre or LaPierre is a surname, and may refer to:
- Dominique Lapierre, French author
- Edmond Lapierre (1866–1960), Canadian politician
- Fabrice Lapierre, Australian athlete
- Jean Lapierre, Canadian television broadcaster and politician
- Judith Lapierre, Canadian professor of nursing, studied at International Space University
- Laurier LaPierre, Canadian journalist, retired broadcaster and senator
- Maxim Lapierre, Canadian hockey player
- Nicolas Lapierre, French race car driver
- Odette Lapierre, Canadian athlete
- Réal Lapierre, Canadian politician
- Wayne LaPierre, American author and gun rights advocate
- Lapierre Bikes, bicycle manufacturer
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