Development of Ringer's Solution
Ringer's saline solution was invented in the early 1880s by Sydney Ringer, a British physician and physiologist. Ringer was studying the beating of an isolated frog heart outside of the body. He hoped to identify the substances in blood that would allow the isolated heart to beat normally for a time. The original solution of inorganic salts was further modified by Alexis Hartmann for the purpose of treating acidosis in children. Hartmann added lactate, which mitigates changes in pH by acting as a buffer for acid. Thus the solution became known as "lactated Ringer's solution" or "Hartmann's solution".
Read more about this topic: Lactated Ringer's Solution
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