La Frontera (Spanish for "the Border") may refer to:
- La Frontera, Spain, a municipality in Spain
- La Frontera, Chile, a geographical region in Chile, bordering on AraucanÃa
- La Frontera (film), a 1991 Chilean film
- La Frontera (band), a Spanish rock band, played at 1994 Caribana Festival
- La Frontera (Round Rock, Texas), a development in Texas, USA
- La Frontera (newspaper), a former newspaper in South Texas, United States