The abbreviation KSU, depending on context, could refer to one of the following:
- The NYSE ticker symbol for the Kansas City Southern Railway
- The IATA code for Kristiansund Airport in Kvernberget, Norway
- In telephony, a key system unit
- Universities:
- Kansas State University in Manhattan, Kansas, USA
- Kazan State University in Kazan, Russia
- Kennesaw State University in Kennesaw, Georgia, USA
- Kent State University in Kent, Ohio, USA
- Kentucky State University in Frankfort, Kentucky, USA
- King Saud University in Riyadh, Saudi Arabia
- Kiev State University in Kiev, Ukraine
- Kun Shan University in Yongkang, Taiwan
Other entities:
- Kunsill Studenti Universitarji, the students'council of a Maltese university
- KSU (band), a 1970s punk rock band from Ustrzyki Dolne, Poland
- Kerala Students Union
- KZSU, a radio station at Stanford University formerly known as KSU