KOC is an abbreviation that can mean:
- Kings of Convenience, a Norwegian indie musical group.
- Knights of Columbus, a Roman Catholic fraternal organization.
- Kodiak College, a college located in Kodiak, Alaska.
- Kuwait Oil Co., one of the biggest oil companies in the world.
- Korean Olympic Committee - represents South Korea in handling international affairs related to the Olympic Movement.
- Knights of Cydonia, a song by the British band Muse.
- Kingdom of Comfort, a Delirious? album.