Kirillov (Russian: Кириллов), or Kirillova (Кириллова; feminine), is a Russian last name and may refer to:
- People
- Alexandre Kirillov (b. 1936), a Russian mathematician
- Alexander Kirillov, Jr., his son, Russian-American mathematician
- Alexander Semyonovich Kirillov (b. 1921), a Soviet aircraft pilot and Hero of the Soviet Union
- Averky Kirillov (1622–1682), a Russian statesman and entrepreneur
- Igor Leonidovich Kirrilov (b. 1932), a Soviet and Russian television presenter and announcer
- Ivan Kirillovich Kirillov (-1747), founded Orenburg, involved in the Bashkir War of 1735-40
- Mikhail Kirillov (1900–1971), a Russian/Soviet actor
- Mikhail Kirillov (1908–1975), a Russian/Soviet cinematographer
- Mikhail Petrovich Kirillov (1918–1988), a Soviet army officer and Hero of the Soviet Union
- Nikolai Kirillov (1914–1993), a Soviet army officer and Hero of the Soviet Union
- Pyotr Kirillov (1910–1955), a Mordvin Soviet writer
- Veniamin Kirillov (1916–1943), a Soviet army officer and Hero of the Soviet Union
- Vladimir Kirillov (1889–1943), a Russian/Soviet poet
- Alexei Nilych Kirillov, character in Dostoevsky novel 'The Possessed'
- Places
- Kirillov (town), a town in Russia