Notable People Named Killian
- Killian Brennan, an Irish footballer player currently with the League of Ireland club Bohemian F.C.
- Edwin Henry Killian (1876–1928), a Major League Baseball pitcher primarily of the Detroit Tigers
- George E. Killian, a sports administrator and currently the president of the International University Sports Federation
- Gustav Killian (1860–1921), a German laryngologist for whom Killian's dehiscence is named
- James Rhyne Killian (1904–1988), the 11th president of the Massachusetts Institute of Technology
- Jerry B. Killian, an officer in the Texas Air National Guard in the early 1970s, to whom Lieutenant George W. Bush was a subordinate
- Robert K. Killian (1919–2005), an American politician from the state of Connecticut.
- Killian K. Van Rensselaer (1763–1845), member of the United States House of Representatives from New York
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