Kamehameha may refer to:
- House of Kamehameha, the dynasty of the Hawaiian Kings
- Kamehameha I (18th-century–1819), first king of the Hawaiian Islands
- Kamehameha Statues
- Kamehameha Day, a Hawaiian public holiday
- Kamehameha II (1797–1824), second king of the Kingdom of Hawaii
- Kamehameha III (1813–1854), King of Hawaii from 1825 to 1854
- Kamehameha IV (1834–1863), the fourth king of Hawaii from 1855 to 1863
- Kamehameha V (1830–1872), reigned as monarch of the Kingdom of Hawaiʻi from 1863 to 1872
- Albert Kamehameha (1858–1862), crown prince of Hawaii
- Kamehameha I (18th-century–1819), first king of the Hawaiian Islands
- Fort Kamehameha, 1907 through World War II defenses of Honolulu
- Kamehameha Hall, the meeting house of the Royal Order of Kamehameha I
- Royal Order of Kamehameha I (decoration), a medal awarded by the Kingdom of Hawaii
- Kamehameha Schools, a college preparatory institution in Hawaii
- USS Kamehameha (SSBN-642), a submarine of the United States Navy
- Kamehameha butterfly or Vanessa tameamea
- Kamehameha, an iconic fictional energy wave employed by several characters in Dragon Ball media