Kainate Receptor - Conductance

Conductance

The ion channel formed by kainate receptors is permeable to sodium and potassium ions. The amount of sodium and potassium the channels allow through their pores per second (their conductance) is similar to that of AMPA channels, at about 20 pS. However, rise and decay times for postsynaptic potentials generated by KARs are slower than for AMPA postsynaptic potentials. Their permeability to Ca2+ is usually very slight but varies with subunits and RNA editing at the tip of the p loop.

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