Presentation
Age of onset is variable. The term 'Juvenile' in the title of Juvenile Polyposis Syndrome refers to the histological type of the polyps rather than age of onset.
Affected individuals may present with rectal bleeding, abdominal pain, diarrhea or anemia. On colonoscopy or sigmoidoscopy polyps that vary in shape or size are present. The polyps can be sessile or pedunculated hamartomatous polyps.
Most juvenile polyps are benign, however, malignancy can occur. Lifetime risk of developing cancers of the gastro-intestinal tract in people with Juvenile Polyposis Syndrome ranges from 9% to 50%.
Read more about this topic: Juvenile Polyposis Syndrome
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