Diagnosis and Testing
Biopsies of the skin may be performed to identify the cleavage that takes place at the dermal-epidermal junction. Another test that can aid in a diagnosis of JEB is the positive Nikolsky’s sign. By applying pressure to the skin, transverse movements can indicate slipping between the dermal and epidermal layers. An easier and more definitive test is through polymerase chain reaction (PCR). This method allows mane and tail samples to be genetically tested for the mutated genes that cause the condition. Hair samples must be pulled, not cut, with roots attached. The test can detect both JEB1 and JEB2. Testing costs around $35.00 US per sample.
Read more about this topic: Junctional Epidermolysis Bullosa (veterinary Medicine)
Famous quotes containing the word testing:
“Bourbon’s the only drink. You can take all that champagne stuff and pour it down the English Channel. Well, why wait 80 years before you can drink the stuff? Great vineyards, huge barrels aging forever, poor little old monks running around testing it, just so some woman in Tulsa, Oklahoma can say it tickles her nose.”
—John Michael Hayes (b.1919)