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- John Hutchinson (Colonel) (1615–1664), leader in the 17th-century Puritan revolt in Britain
- John Hutchinson (industrialist) (1825–1865), established the first chemical factory in Widnes, England
- John Duflon Hutchison, British merchant and founder of John D. Hutchison Company, now Hutchison Whampoa
- John Hutchinson (academic) (born 1949), British academic in the Department of Government at the London School of Economics
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