Jocasta or Iocaste (Ἰοκάστη) is a character in Greek mythology.
It may also refer to:
- Iocaste (moon), a moon of Jupiter
- Jocasta (band), a 1990s britpop band
- Jocasta (character of Rome), a minor character in the TV series Rome
- Jocasta (comics), a Marvel Comics character
- Jocaste (crustacean), a shrimp genus
- Jocasta Nu, a minor Star Wars character
- 899 Jokaste, a minor planet orbiting the Sun