Jefferson Smith may refer to:
- Jefferson ("Soapy") Smith (1860–1898), American con artist and gangster
- Jefferson Smith (politician), member of the Oregon House of Representatives and the founder of the Bus Project
- Jefferson Smith, the main character in the 1939 film Mr. Smith Goes to Washington, portrayed by James Stewart
Famous quotes related to jefferson smith:
“Jefferson Smith: I hate to stand here and try your patience like this, but either I’m dead right or I’m crazy.
Senator MacPherson: You wouldn’t care to put that to a vote, would you, Senator?”
—Sidney Buchman (1902–1975)