Fictional Characters
- Janine Butcher, in EastEnders
- Janine Nebeski, in Bad Girls
- Janine (Pokémon), in the Pokémon universe
- Janine Melnitz, in the Ghostbusters films
- Janine Stifler, aka Stifler's Mom, in the American Pie film series
- Janine, a recurring character in sitcom Friends played by Elle Macpherson
- Janine, a fictional character from Witch and Wizard, a novel by James Patterson
- Janine, the previous name of Ofwarren, a fictional character from The Handmaid's Tale, a novel by Margaret Atwood
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