James Young Simpson - Obstetric Anaesthesia

Obstetric Anaesthesia

Sir Humphry Davy used the first anaesthetic in 1799, nitrous oxide (laughing gas). Robert Liston's ether was initially dismissed as an anaesthetic because it irritated the lungs of the patients. In 1847, Simpson discovered the properties of chloroform during an experiment with friends in which he learnt that it could be used to put one to sleep. Dr Simpson and two of his friends, Drs Keith and Duncan used to sit every evening in Dr Simpson's dining room to try new chemicals to see if they had any anaesthetic effect. On 4 November 1847 they decided to try a ponderous material named chloroform that they had previously ignored. On inhaling the chemical they found that a general mood of cheer and humour had set in. But suddenly all of them collapsed only to regain consciousness the next morning. Simpson knew, as soon as he woke up, that he had found something that could be used as an anaesthetic. They soon had Miss Petrie, Simpson's niece, try it. She fell asleep soon after inhaling it while singing the words, "I am an angel!". It was very much up to chance that Simpson survived the chloroform dosage he administered to himself. If he had inhaled too much, subsequently passing away from an overdose, chloroform would have been seen as a dangerous substance. However, if Simpson had inhaled slightly less it would not have put him to sleep. It was his willingness to explore the possibilities of the substance that established his career as a pioneer in the field of medicine.

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