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- James Moore (engineer) (1830–1887), Australian railway engineer
- James Moore (Continental Army officer) (1729–1777), American Revolutionary War general
- James Edward Moore (1902–1986), U.S. Army general
- James F. Moore, Senior Fellow at Harvard Law School's Berkman Center for Internet and Society
- James Moore (furniture designer) (died 1726), English cabinet maker
- James T. Moore (1952–2006), American atmospheric scientist from Cornell University and Saint Louis University
- James Beach Moore (1842–1931), Canadian Quaker
- Jimmy Moore (bishop) (1933–2005), Irish clergyman
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