The Ivanov reaction is the chemical reaction of the dianions (endiolates) of aryl acetic acids (Ivanov reagents) with electrophiles, primarily carbonyl compounds or isocyanates. The reaction was named after the Bulgarian organic chemist, Academician Dimitar Ivanov, who discovered it.
Ivanov reagents (dianions of aryl acetic acids) react with many electrophiles, including aldehydes, ketones, isocyanates, and alkyl halides. The product does not usually spontaneously decarboxylate, but it is possible with some reagents.
The Ivanov reaction is known to proceed through the Zimmerman-Traxler model transition state. Toulec et al. have investigated the reaction rates and kinetics.
Famous quotes containing the word reaction:
“An actor must communicate his author’s given message—comedy, tragedy, serio- comedy; then comes his unique moment, as he is confronted by the looked-for, yet at times unexpected, reaction of the audience. This split second is his; he is in command of his medium; the effect vanishes into thin air; but that moment has a power all its own and, like power in any form, is stimulating and alluring.”
—Eleanor Robson Belmont (1878–1979)