Ista may refer to:
- Kevyn Ista (born 1984), Belgian road bicycle racer
- -ista, a pejorative suffix in English, regular suffix in Spanish, Portuguese, Italian, etc.
- Ista (Bangladesh), a place in the Jessore District, Khulna Division of Bangladesh
- Ista Hold, Ista Island, fictional locations in Anne McCaffrey's Dragonriders of Pern, see Holds of Pern
- the heroine of Paladin of Souls, a novel by Lois McMaster Bujold
ISTA or Ista may also refer to:
- International Safe Transit Association, an global organization that writes test procedures for performance package testing
- International School of Theatre Anthropology (since 1979), based in the Odin Teatret, Denmark
- Internet Sacred Text Archive (since 1999), archive of cultural public domain texts
- International Seed Testing Association, co-founded by the National Institute of Agricultural Botany
- Indiana State Teachers Association, in Indiana
- International Schools Theatre Association, based in the UK, networked in schools such as The British School, New Delhi or KoƧ School
- International Society for Technology Assessment, related to Bryan Jennett, Fred Polak
- Ista Pharmaceuticals or ISTA Pharmaceuticals, related to Calvin A. Grant, Hyaluronidase
- International School of Traditional Aikido an Aikido organisation founded in France.