Ischemia - Treatment

Treatment

Decrease in body temperature reduces the aerobic metabolic rate of the affected cells, reducing the immediate effects of hypoxia. Reduction of body temperature also reduces the inflammation response and reperfusion injury.

For frostbite injuries, limiting thawing and warming of tissues until warmer temperatures can be sustained may reduce reperfusion injury.

For blood clots, administration of "clot-buster" drugs such as Alteplase within the critical time period, together with some collateral circulation to the ischemic area is a main factor in patient recoveries.

Other drug therapies such as cannabinoids and hydrogen sulfide are being researched for limiting ischemic injuries.

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