Causes
In primary chronic intestinal pseudo-obstruction (the majority of chronic cases), the condition may be caused by a injury to the smooth muscle (myopathic) or the nervous system (neuropathic) of the gastrointestinal tract.
In some cases there appears to be a genetic association. One form has been associated with DXYS154.
Secondary chronic intestinal pseudo-obstruction can occur as a consequence of a number of other conditions, including Kawasaki disease, Parkinson's disease, Chagas' Disease, Hirschsprung's Disease, Intestinal Hypoganglionosis, collagen vascular diseases, endocrine disorders and use of certain medications. The term may be used synonymously with Enteric neuropathy if a neurological cause is suspected.
Read more about this topic: Intestinal Pseudoobstruction