Interspersed Repeat - Intrachromosomal and Interchromosomal Gene Conversion

Intrachromosomal and Interchromosomal Gene Conversion

Gene conversion acts on DNA sequence homology as its substrate. There is no requirement that the sequence homologies lie at the allelic positions on their respective chromosomes or even that the homologies lie on different chromosomes. Gene conversion events can occur between different members of a gene family situated on the same chromosome. When this happens, it is called intrachromosomal gene conversion as distinguished from interchromosomal gene conversion. The effect of homogenizing DNA sequences is the same.

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