Follicular Lymphoma International Prognostic Index (FLIPI)
Given the success of the IPI for intermediate grade lymphomas, an effort was undertaken to develop a similar prognostic index for the most common low-grade lymphoma, follicular lymphoma. The prognostic factors that emerged from this were: age, stage, number of lymph node areas involved, serum hemoglobin level, and serum LDH.
One point is assigned for each of the following adverse prognostic factors:
- Age greater than 60 years
- Stage III or IV disease
- Greater than 4 lymph node groups involved
- Serum hemoglobin less than 12 g/dL
- Elevated serum LDH
The sum of the points allotted correlates with the following risk groups:
- Low risk (0-1 points) - 5 and 10-year survivals of 91% and 71%, respectively
- Intermediate risk (2 points) - 5 and 10-year survivals of 78% and 51%, respectively
- High risk (3-5 points) - 5 and 10-year survivals of 53% and 36%, respectively
Read more about this topic: International Prognostic Index
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