International AIDS Vaccine Initiative - Discoveries

Discoveries

In September 2009, a global group of researchers led by IAVI published a study in the journal Science identifying PG9 and PG16, two highly powerful broadly neutralizing antibodies against a wide variety of HIV variants. The site on the virus to which PG9 and PG16 attach revealed a vulnerability on HIV. PG9 and PG16 were the first new broadly neutralizing antibodies against HIV discovered in more than a decade and are the result of a global effort launched in 2006. Several more have broadly neutralizing antibodies to HIV haven been isolated since this discovery, and researchers are now using this information to guide the design and development of new and perhaps more potent AIDS vaccine candidates.

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