Hybrid Inviability

Hybrid inviability is a post-zygotic barrier, which reduces a hybrid's capacity to mature into a healthy, fit adult. The relatively low health of these hybrids relative to pure-breed individuals prevents gene flow between species. Thus, hybrid inviability acts as an isolating mechanism, limiting hybridization and allowing for the differentiation of species.

The barrier of hybrid inviability occurs after mating species overcome pre-zygotic barriers (behavioral, mechanical, etc.) to produce a zygote. The barrier emerges from the cumulative effect of parental genes; these conflicting genes interfere with the embryo's development and prevents its maturation. Most often, the hybrid embryo dies before birth. However, sometimes, the offspring develops fully with mixed traits, forming a frail, often infertile adult. This hybrid displays reduced fitness, marked by decreased rates of survival and reproduction relative to the parent species. The offspring fails to compete with purebred individuals, limiting genes flow between species.

Read more about Hybrid Inviability:  Evolution of Hybrid Inviability in Tetrapods