Human Brain Mapping - Chemotherapy

Chemotherapy

• Chemotherapy - the use of drugs to kill or alter cancer cells. Chemotherapy is not an effective initial treatment for low-grade brain tumors, mostly because standard chemotherapy drugs cannot pass through the blood-brain barrier. Chemotherapy for brain tumors is typically administered following surgery or radiation therapy. Local delivery (placement of the drugs within or around the brain tumor) is typically necessary. Injection into cerebrospinal fluid is also a less invasive possibility.
• Post-chemotherapy cognitive impairment - (also known as chemotherapy-induced cognitive dysfunction, chemo brain, or chemo fog) describes the cognitive impairment that impacts approximately 20–30% of people who undergo general chemotherapy.