HSH may refer to:
- The Albanian code for Hekurudha Shqiptare in Albania
- The IATA code for Henderson Executive Airport in Henderson, Nevada, USA
- Her Space Holiday, American indie rock group
- His/Her Serene Highness, two manners of address
- Hekurudha Shqiptare, Albania's national rail system
- H-S-H, an electric guitar pickup configuration that includes humbucker, single and humbucker pickups.
- Federation of Norwegian Commercial and Service Enterprises, abbreviated HSH in Norwegian
- Hudson Street Hooligans, supporters of the Columbus Crew
- HSH also stands for "Home, Sweet Home"
- HSH Group, The Hongkong and Shanghai Hotels, Limited