Hox Gene - Colinearity of Hox Genes

Colinearity of Hox Genes

In some organisms, especially vertebrates, the various Hox genes are situated very close to one another on the chromosome in groups or clusters. Interestingly, the order of the genes on the chromosome is the same as the expression of the genes in the developing embryo, with the first gene being expressed in the anterior end of the devesm. The reason for this colinearity is not yet completely understood. The diagram above shows the relationship between the genes and protein expression in flies.

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