Hooft or 't Hooft may refer to:
- Cornelis Hooft (1547–1627), Dutch statesman
- Pieter Corneliszoon Hooft (1581–1647), Dutch historian, poet and playwright
- Catharina Hooft (1618–1691), woman of the Dutch Golden Age
- Willem Visser 't Hooft (1900–1985), Dutch theologian and the first secretary general of the World Council of Churches
- Haas Visser 't Hooft (1905–1977), Dutch field hockey player
- Gerard 't Hooft (born 1946), Dutch theoretical physicist
- Jotie T'Hooft (1956–1977), Flemish Belgian neo-romantic poet
- Hooft (island) an island in the IJmeer