Homology Directed Repair

Homology directed repair (HDR) is a mechanism in cells to repair double strand DNA lesions. This repair mechanism can only be used by the cell when there is a homologue piece of DNA present in the nucleus, mostly in G2 and S phase of the cell cycle. When the homologue DNA piece is absent, another process called non-homologous end joining (NHEJ) can take place instead.

Read more about Homology Directed Repair:  Cancer Suppression, Biological Pathway, Reference and Further Reading

Famous quotes containing the words directed and/or repair:

    If Mr. Vincent Price were to be co-starred with Miss Bette Davis in a story by Mr. Edgar Allan Poe directed by Mr. Roger Corman, it could not fully express the pent-up violence and depravity of a single day in the life of the average family.
    Quentin Crisp (b. 1908)

    It is not only a question of who is responsible for very young children. There is no longer anyone home to care for adolescents and the elderly. There is no one around to take in the car for repair or to let the plumber in. Working families are faced with daily dilemmas: Who will take care of a sick child? Who will go to the big soccer game? Who will attend the teacher conference?
    Fran Sussner Rodgers (20th century)