Homology directed repair (HDR) is a mechanism in cells to repair double strand DNA lesions. This repair mechanism can only be used by the cell when there is a homologue piece of DNA present in the nucleus, mostly in G2 and S phase of the cell cycle. When the homologue DNA piece is absent, another process called non-homologous end joining (NHEJ) can take place instead.
Read more about Homology Directed Repair: Cancer Suppression, Biological Pathway, Reference and Further Reading
Famous quotes containing the words directed and/or repair:
“At present the globe goes with a shattered constitution in its orbit.... No doubt the simple powers of nature, properly directed by man, would make it healthy and a paradise; as the laws of man’s own constitution but wait to be obeyed, to restore him to health and happiness.”
—Henry David Thoreau (1817–1862)
“It is not difficult to deceive the first time, for the deceived possesses no antibodies; unvaccinated by suspicion, she overlooks latenesses, accepts absurd excuses, permits the flimsiest patchings to repair great rents in the quotidian.”
—John Updike (b. 1932)