Hofstadter may refer to:
People with the surname Hofstadter:
- Albert Hofstadter (1910–1989), American philosopher
- Douglas Hofstadter (born 1945), American professor, author of Gödel, Escher, Bach and son of Robert Hofstadter
- Leonard Hofstadter, a fictitious character from the television series, The Big Bang Theory
- Richard Hofstadter (1916–1970), American historian
- Robert Hofstadter (1915–1990), American Nobel Prize-winner in physics
Other:
- Hofstadter sequence, an integer sequence
- Hofstadter-Moebius loop, a fictional condition that affected HAL 9000, a fictional computer
- Hofstadter's butterfly, a fractal
- Hofstadter's law, "It always takes longer than you expect ..."
- Hofstadter point, a triangle center