Alleles
| DQ | DQ | DQ | Freq | |||||
|---|---|---|---|---|---|---|---|---|
| Serotype | cis-isoform | Subtype | A1 | B1 | % | rank | ||
| DQ8 | α3-β8 | 8.1 | 0301 | 0302 | 9. | 62 | 6th | |
| 0302♠ | 0302 | 0. | 93 | |||||
| ♠DQA1*0302 & *0303 not resolved | ||||||||
DQ8 is determined by the antibody recognition of β8 and is complicated by the fact that DQ8 recognizes some HLA-DQB1*03 encoded isoforms well, partially or not well at all (See serology) DQ β3.2 and β3.5 are best recognized as DQ8. These split antigens are the allele products of the DQB1*0302 and DQB1*0305, respectively.
Read more about this topic: HLA-DQ8