HLA-A34 - A34-B Haplotypes

A34-B Haplotypes

A34 is in strong linkage disequilibrium in many areas of the world, but particularly SE Asia and Oceania. The most prominent of these haplotypes is A34-Cw11(1)-B56. This haplotype is found from Western Australia to Taiwan to New Zealand indicating a recent genetic linkage between these peoples.

Another frequently found haplotype is the A34-B61 (A*3401:Cw*04:B*B4002) haplotype. This haplotype has a similar distribution as A34-B56.

These haplotypes indicate that long range/oversees migrations were taking place in Austronesias (late paleolithic) prehistory.

HLA A34-Cw11-B56
A*3401:Cw*0102:B*5601
freq
ref. Population (%)
Ami (Indig. Taiwan) 19.9
Highlanders (PNG) 10.6
Maori (New Zealand) 5.6
Indigenous Australia 4.1
Puyuma (Indig. Taiwan) 4.0

Read more about this topic:  HLA-A34