Hillis may refer to:
People with the given name Hillis:
- Hillis Layne (1918-2010), an American third baseman in Major League Baseball
- J. Hillis Miller (born 1928), an American literary critic
- J. Hillis Miller, Sr. (1899-1953), the fourth President of the University of Florida
- Yda Hillis Addis (born 1857), an American writer
People with the surname Hillis:
- Ali Hillis (born 1978), an American actress
- David Hillis (21st century), a prominent American herpetologist and systematic biologist
- Dick Hillis (1913-2005), an American Protestant Christian missionary to China
- Elwood Hillis (born 1926), a United States Army soldier
- Horace Hillis (20th century), an American politician
- Mack Hillis, a Major League Baseball second baseman
- Margaret Hillis (1921-1998), an American conductor
- Newell Dwight Hillis (1858-1929), an American writer
- Norman Hillis (21st century), a Northern Ireland politician
- Peyton Hillis (born 1986), an American football fullback
- Rib Hillis (born 1971), an American soap opera actor
- Ron Hillis (born 1906), an Australian rules footballer
- W. Daniel Hillis (born 1956), an American inventor, entrepreneur and author