Colony-forming Units
There are various kinds of colony-forming units:
- Colony-forming unit lymphocyte (CFU-L)
- Colony-forming unit erythrocyte (CFU-E)
- Colony-forming unit granulo-monocyte (CFU-GM)
- Colony-forming unit megakaryocyte (CFU-Me)
- Colony-forming unit Basophil (CFU-B)
- Colony-forming unit Eosinophil (CFU-Eo)
The above CFUs are based on the lineage. Another CFU, the colony-forming unit–spleen (CFU–S) was the basis of an in vivo clonal colony formation, which depends on the ability of infused bone marrow cells to give rise to clones of maturing hematopoietic cells in the spleens of irradiated mice after 8 to 12 days. It was used extensively in early studies, but is now considered to measure more mature progenitor or Transit Amplifying Cells rather than stem cells.
Read more about this topic: Hematopoietic Stem Cell
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